Did you know...? According to Dr Ross Hauser, "one of the most serious adverse reactions to NSAIDs ( Rimadyl, Metacam, Deramaxx and Previcox or Galliprant) is that as a class of compounds they cause the breakdown of articular cartilage, thereby accelerating osteoarthritis, the very disease for which they are most commonly prescribed! The pathogenesis of osteoarthritis is accelerated by NSAIDs." Even the authors of the esteemed Small Animal Surgery textbook assert, "Most NSAIDs interfere with chondrocyte (cartilage cells) glycosaminoglycan synthesis and therefore should be used continuously only for a short time." They suggest chondroprotective food additives, which may decrease joint inflammation. The same authors suggest gastroprotective medications alongside NSAIDs. Journal of Prolotherapy Volume 2 Issue 1 February 2010 Small Animal Surgery Mosby Fossum 1997 p.945 | 
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