The 2 busiest days at animal shelters across the country are July 5th and January 1st. Why? Animals who panic and run during holiday fireworks! Check out our 5 Step Guide to Helping Your Pet Survive Firework Season. And make sure to grab Cannimal's best selling RELAX Formula in time for 4th of July! | | | RELAX FORMULA Full Spectrum CBD with Passionflower Extract *Passion flower has many constituents, including flavonoids, maltol, and indole alkaloids. Active ingredients include, chrysin, vitexin, coumerin, and umbelliferone(Spinella, 2001). Chrysin is the most studied component. Along with other flavonoids, chrysin has been shown to bind to benzodiazepine receptors sites and acts as an agonist for GABA activity, especially at A type GABA receptors. This has an inhibitory effect on the brain, accounting for passion flower's anxiolytic properties. In animal studies, psychoactive effects of passion flower were reversed by benzodiazepine antagonists, and the overall effect in the brain has been compared to that of diazepam (Valium) (Wolfman et al., 1994). | | | |